DDS sensitivity of mycobacteria. Antagonistic effect of PABA for M. ulcerans and M. kansasii.
نویسندگان
چکیده
In the words of Shepard the great sensitivity of Mycobacterium leprae to 4-4'-diaminodiphenyl sulfone (DDS) was at first surprising (13) . The DDS sensitivity of some other mycobacteria was shown by Karlson ( 3) to be much higher. Since many new species of mycobacteria have been described since 1963, we thought it would be useful to tes t these and to determine the minimal inhibitory concentration ( MIC ) for the most sensitive ones. At the same time we made some observations on the antagonistic effect of paraaminobenzoic acid (PABA) on DDS, using M. ulcerans, M. kansasii, and M. gastri as test organisms.
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عنوان ژورنال:
- International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association
دوره 36 4 شماره
صفحات -
تاریخ انتشار 1968